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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Unisom

$4.530 tablets/25 mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Doxylamine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Doxylamine every time. What are you waiting for? Claim your prescription drug card now!

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Doxylamine volume of distribution

A single oral dose of doxylamine succinate 25 mg was administered to 21 young (20 to 43 years) and 22 elderly (60 to 87 years) volunteers. Multiple plasma doxylamine concentrations were determined during a 30-hour period after each dose. Elderly and young women did not differ significantly in peak plasma doxylamine concentration (Cmax) [116 vs 103 micrograms/L], time to Cmax (tmax), elimination half-life (12.2 vs 10.1 h), volume of distribution (179 vs 176 L) or clearance (191 vs 218 ml/min). Cmax (107 vs 108 micrograms/L) and tmax (2.1 vs 1.6 h) also did not differ between elderly and young men.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Doxylamine

Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

Doxylamine mechanism of action

Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 nbsp;receptors. It also has substantial sedative and anticholinergic effects.

Dosage forms of Doxylamine

Capsule, gelatin coatedoral
Tablet, effervescentoral

Prescription Generics


International Brands

7 Select Night Time Relief


2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine 2-Dimethylaminoethoxyphenylmethyl-2-picoline


7 Eleven

CAS number






Affected organisms

Humans and other mammals

Indication of Doxylamine

Used alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

Toxicity of Doxylamine

Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

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