Save up -80% on Drotrecogin alfa

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Drotrecogin alfa

Xigris 5 mg vial

$370.42

vial

* price without discount in nearest pharmacy. Price may vary.

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Drotrecogin alfa volume of distribution

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What is Drotrecogin alfa

Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.

Drotrecogin alfa mechanism of action

Activated protein C combines with protein S on platelet surfaces and then degrades factor Va and factor VIIIa, thereby reducing blood coagulability.

Dosage forms of Drotrecogin alfa

FormRouteStrength
Powder for solution for infusionIntravenous use20 mg
Powder for solution for infusionIntravenous use5 mg
Powder for solutionintravenous20 mg
Prescription Generics

false

International Brands

Xigris (20mg/vial)

Synonyms

Activated protein C Blood coagulation factor XIV (human)

Manufacturers

Eli Lilly Canada Inc

CAS number

98530-76-8

UNII

JGH8MYC891

State

liquid

Affected organisms

Humans and other mammals

Indication of Drotrecogin alfa

For reduction of mortality in patients with severe sepsis.

Toxicity of Drotrecogin alfa

RX24 Drugs Disclaimer: before buying a Drotrecogin alfa on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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