Save up -80% on Drotrecogin alfa
Note: this is a drug discount program, not an insurance plan.
2018 Price of Drotrecogin alfa
Xigris 5 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Drotrecogin alfa volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.
Drotrecogin alfa mechanism of action
Activated protein C combines with protein S on platelet surfaces and then degrades factor Va and factor VIIIa, thereby reducing blood coagulability.
Dosage forms of Drotrecogin alfa
|Powder for solution for infusion||Intravenous use||20 mg|
|Powder for solution for infusion||Intravenous use||5 mg|
|Powder for solution||intravenous||20 mg|
Activated protein C Blood coagulation factor XIV (human)
Eli Lilly Canada Inc
Humans and other mammals
Indication of Drotrecogin alfa
For reduction of mortality in patients with severe sepsis.
Toxicity of Drotrecogin alfa
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