Save up -80% on Drotrecogin alfa
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Price of Drotrecogin alfa
Xigris 5 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Drotrecogin alfa volume of distribution
What is Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.
Drotrecogin alfa mechanism of action
Activated protein C combines with protein S on platelet surfaces and then degrades factor Va and factor VIIIa, thereby reducing blood coagulability.
Dosage forms of Drotrecogin alfa
|Powder for solution for infusion||Intravenous use||20 mg|
|Powder for solution for infusion||Intravenous use||5 mg|
|Powder for solution||intravenous||20 mg|
Activated protein C
Blood coagulation factor XIV (human)
Eli Lilly Canada Inc
Humans and other mammals
Indication of Drotrecogin alfa
For reduction of mortality in patients with severe sepsis.
Toxicity of Drotrecogin alfa
Disclaimer: before buying a Drotrecogin alfa on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.