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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Dutasteride

Avodart 0.5 mg softgel

$4.06

softgel capsule

* price without discount in nearest pharmacy. Price may vary.

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Dutasteride volume of distribution

* 300 to 500 L

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What is Dutasteride

Dutasteride belongs to a class of drugs called 5-alpha-reductase inhibitors, which block the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT). Finasteride also belongs to this group, but while dutasteride inhibits both isoforms of 5-alpha reductase, finasteride inhibits only one. Even so, a clinical study done by GlaxoSmithKline, the EPICS trial, did not find dutasteride to be more effective than finasteride in treating BPH. (Wikipedia)

Dutasteride mechanism of action

Dutasteride inhibits the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT), which is the androgen primarily responsible for the initial development and subsequent enlargement of the prostate gland. Testosterone is converted to DHT by the enzyme 5 alpha-reductase, which exists as 2 isoforms, type 1 and type 2. Dutasteride is a competitive and specific inhibitor of both type 1 and type 2 5 alpha-reductase isoenzymes, with which it forms a stable enzyme complex. Dissociation from this complex has been evaluated under iin vitro /i and iin vivo /i conditions and is extremely slow. Dutasteride does not bind to the human androgen receptor.

Dosage forms of Dutasteride

DrugDosageQuantityPrice
Avodart0.5mg30 Capsule$68.00
Avodart0.5mg90 Capsule$71.30
Dutasteride/Tamsulosin0.5/0.4mg100 Capsule$90.00
Jalyn0.5/0.4mg90 Capsule$278.00
Prescription Generics

false

International Brands

Act Dutasteride

Synonyms

(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide alpha,alpha,alpha,Alpha’,alpha’,alpha’-hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2′,5′-xylidide

Manufacturers

Actavis Pharma Company

CAS number

164656-23-9

UNII

O0J6XJN02I

State

solid

Affected organisms

Humans and other mammals

Indication of Dutasteride

For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland to improve symptoms, and reduce the risk of acute urinary retention and the need for surgery.

Toxicity of Dutasteride

RX24 Drugs Disclaimer: before buying a Dutasteride on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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