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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Echothiophate

Phospholine iodide 0.125%



* price without discount in nearest pharmacy. Price may vary.

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Echothiophate volume of distribution

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What is Echothiophate

A potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.

Echothiophate mechanism of action

Echothiophate Iodide is a long-acting cholinesterase inhibitor for topical use which enhances the effect of endogenously liberated acetylcholine in iris, ciliary muscle, and other parasympathetically innervated structures of the eye. Echothiophate iodide binds irreversibly to cholinesterase, and is long acting due to the slow rate of hydrolysis by cholinesterase. It causes miosis, increase in facility of outflow of aqueous humor, fall in intraocular pressure, and potentiation of accommodation.

Dosage forms of Echothiophate

Liquid; powder for solutionophthalmic3 mg
Powder for solutionophthalmic12.5 mg
Powder for solutionophthalmic3 mg
Prescription Generics


International Brands

Phospholine Iodide – Liq Pws 3mg/5ml


2-(Diethoxyphosphorylsulfanyl)ethyl-N,N,N-trimethylazanium iodide Echothiophate


Storz, Division Of Wyeth Ayerst Canada Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Echothiophate

For use in the treatment of subacute or chronic angle-closure glaucoma after iridectomy or where surgery is refused or contraindicated.

Toxicity of Echothiophate

Side effects include blurred vision or change in near or distant vision and eye pain. LD50: 174 mcg/kg in rats. (MSDS)

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