Save up -80% on Efmoroctocog alfa

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Eloctate

$556.701 kit (single dose) 250iu
price without discount in nearest pharmacy. Price may vary.

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Efmoroctocog alfa volume of distribution

Following a single intravenous dose of 50 IU/kg in previously-treated adult patients with severe haemophilia A, mean volume of distribution at steady state (Vss) ranged from 49.1 to 52.6 mL/kg. Mean Vss in adolescent patients 12 to 18 years of age ranged from 57.6 to 59.4mL/kg. Mean Vss in pediatric patients < 12 years of age ranged from 49.5 to 63.1 mL/kg.

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What is Efmoroctocog alfa

Efmoroctocog alfa is a long-acting, fully-recombinant factor VIII Fc fusion protein.

Efmoroctocog alfa mechanism of action

Factor VIII exists in a circulating protein complex consisting of two molecules via a non-covalent binding interaction; Factor VIII and von Willebrand factor. This complex remains inactive until the coagulation cascade is initiated, which activated factor VIII. Factor VIII is released from the protein complex upon activation and acts as a cofactor for factor IX-mediated conversion of factor X to activated factor X on phospholipid surfaces.

Dosage forms of Efmoroctocog alfa

Eloctate250iu1 kit (single dose)$547

Prescription Generics


International Brands



Antihemophilic Factor (Recombinant BDD), FC Fusion Protein Antihemophilic factor (recombinant, FC fusion protein)


Biogen Canada Inc

CAS number






Affected organisms

Indication of Efmoroctocog alfa

For the treatment of Haemophilia A.

Toxicity of Efmoroctocog alfa

Based on the findings from acute and repeated dose toxicity studies, efmoroctocog alfa displays no special hazard for humans. Studies to assess the genotoxicity, carcinogenicity, toxicity to reproduction or embryo-foetal development of efmoroctocog alfa have not been conducted. In a placental transfer study, efmoroctocog alfa has been shown to cross the placenta in small amounts in mice.

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