Save up -80% on Elbasvir
Note: this is a drug discount program, not an insurance plan.
2018 Price of Elbasvir
* price without discount in nearest pharmacy. Price may vary.
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Elbasvir volume of distribution
Estimated apparent volume of distribution of elbasvir is approximately 680 L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Elbasvir
Elbasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural protein 5A (NS5A). Although NS5A has no known enzymatic function, it has been shown to have multiple functions at various stages of the life cycle, including viral replication, virion assembly, and use within multi-protein binding complexes. Combining elbasvir with other drugs that target other points of the viral life cycle and with non-overlapping resistance profiles results in increased potency and an improved barrier to resistance. Elbasvir is currently approved for use in combination with grazoprevir (as the combination product Zapatier) for the treatment of chronic hepatitis C genotypes 1 and 4.
Elbasvir mechanism of action
Elbasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural protein 5A (NS5A), which is essential for viral RNA replication and virion assembly. By combining two direct-acting antiviral agents with distinct mechanisms of action and non-overlapping resistance profiles (elbasvir and grazoprevir) into the fixed dose combination product Zapatier, this medication targets HCV at multiple steps in the viral lifecycle with improved resistance rates.
Dosage forms of Elbasvir
|Tablet, film coated||oral|
Merck Canada Inc
Indication of Elbasvir
Elbasvir, when used in combination with grazoprevir as the combination product Zepatier, is indicated for use with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 or 4 infection in adults.
Toxicity of Elbasvir
The most commonly reported adverse reactions during clinical trials were fatigue, headache, anemia, and nausea.
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