Save up -80% on Enfuvirtide

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Enfuvirtide

Fuzeon convenience kit

$3062.23

kit

* price without discount in nearest pharmacy. Price may vary.

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Enfuvirtide volume of distribution

* 5.5 . 1.1 L

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What is Enfuvirtide

Enfuvirtide is a 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. It is an N-terminal acetylated, C-terminal amide. As an HIV fusion inhibitor, it is the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.

Enfuvirtide mechanism of action

Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes. It works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected. Enfuvirtide is a biomimetic peptide that was rationally designed to mimic components of the HIV-1 fusion machinery and displace them, preventing normal fusion. ; ;

Dosage forms of Enfuvirtide

FormRouteStrength
Kit
Powder and solvent for solution for injectionSubcutaneous use90 mg/ml
Powder for solutionsubcutaneous108 mg
Prescription Generics

false

International Brands

Fuzeon

Synonyms

Envelope polyprotein GP160 precursor[Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41]

Manufacturers

Hoffmann La Roche Limited

CAS number

159519-65-0

UNII

19OWO1T3ZE

State

liquid

Affected organisms

Human Immunodeficiency Virus

Indication of Enfuvirtide

Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.

Toxicity of Enfuvirtide

RX24 Drugs Disclaimer: before buying a Enfuvirtide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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