Save up -80% on Epinephrine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Epipen
|$121.50||1 package (2 auto-injectors)/0.3 mg|
|price without discount in nearest pharmacy. Price may vary.|
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Epinephrine volume of distribution
Area under the plasma concentration versus time curve was approximately 2089 to 2610 pg x hour/ml. Peak exogenous epinephrine concentration was estimated to be 286 to 335 pg/ml. Clearance was 764,508 ml/hour and volume of distribution was 0.4 liter/kg (0.006 liter/kg).
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Epinephrine
The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.
Epinephrine mechanism of action
Epinephrine works via the stimulation of alpha and beta-1 adrenergic receptors, and a moderate activity at beta-2 adrenergic receptors.
Dosage forms of Epinephrine
|Injection||intramuscular; intraocular; subcutaneous||1 mg/mL|
2% Lidocaine and Epinephrine 1:100,000 Injection USP
(-)-(R)-Epinephrine (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
Alveda Pharmaceuticals Inc
Humans and other mammals
Indication of Epinephrine
Used to treat anaphylaxis and sepsis. Also one of the body’s main adrenergic neurotransmitters.
Toxicity of Epinephrine
Skin, LD sub50 /sub = 62 mg/kg (rat)
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What is EpiPen?
EpiPen is an injection containing adrenaline, a chemical that constricts blood vessels and opens the airways in the lungs. These effects can reverse serious low blood pressure, wheezing, severe itching, hives, and other symptoms of an allergic reaction.
EpiPen is used to treat severe allergic reactions (anaphylaxis) to insect bites or bites, food, drugs and other allergens. Epinephrine is also used to treat exercise-induced anaphylaxis.
Epinephrine autoinjectors, such as the EpiPen and EpiPen Jr., may be on hand for self-injection by a person with a history of a severe allergic reaction (anaphylaxis).
Seek emergency medical attention even after using an EpiPen to treat a severe allergic reaction. EpiPen effects may wear out after 10 or 20 minutes. You will need to receive further treatment and observation.
Before using the EpiPen a second time, tell your doctor if your first injection has a serious side effect, such as increased difficulty breathing or dangerously high blood pressure (severe headache, blurred vision, buzzing in the ears, anxiety, confusion, chest pain , shortness of breath, breathing, uneven heartbeat, attack).