Save up -80% on Epirubicin
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Price of Epirubicin
Ellence 2 mg/ml vial
* price without discount in nearest pharmacy. Price may vary.
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Epirubicin volume of distribution
* 21 2 L/kg (60 mg/m2 Dose)
* 27 11 L/kg (75 mg/m2 Dose)
* 23 7 L/kg (120 mg/m2 Dose)
* 21 7 L/kg (150 mg/m2 Dose)
What is Epirubicin
An anthracycline which is the 4 #39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA. (PubChem)
Epirubicin mechanism of action
Epirubicin has antimitotic and cytotoxic activity. It inhibits nucleic acid (DNA and RNA) and protein synthesis through a number of proposed mechanisms of action: Epirubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes. It also interferes with DNA replication and transcription by inhibiting DNA helicase activity.
Dosage forms of Epirubicin
Pharmacia And Upjohn Company Llc
Humans and other mammals
Indication of Epirubicin
For use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer.
Toxicity of Epirubicin
bone marrow aplasia, grade 4 mucositis, and gastrointestinal bleeding
Disclaimer: before buying a Epirubicin on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.