Save up -80% on Epirubicin

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Epirubicin

Ellence 2 mg/ml vial

$5.38

ml

* price without discount in nearest pharmacy. Price may vary.

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Epirubicin volume of distribution

* 21 2 L/kg (60 mg/m2 Dose) * 27 11 L/kg (75 mg/m2 Dose) * 23 7 L/kg (120 mg/m2 Dose) * 21 7 L/kg (150 mg/m2 Dose)

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What is Epirubicin

An anthracycline which is the 4 #39;-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

Epirubicin mechanism of action

Epirubicin has antimitotic and cytotoxic activity. It inhibits nucleic acid (DNA and RNA) and protein synthesis through a number of proposed mechanisms of action: Epirubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes. It also interferes with DNA replication and transcription by inhibiting DNA helicase activity.

Dosage forms of Epirubicin

FormRouteStrength
Injectionintravenous2 mg/mL
Injectionintravenous200 mg/100mL
Injectionintravenous50 mg/25mL
Prescription Generics

false

International Brands

Ellence

Synonyms

4′-Epiadriamycin Epiadriamycin

Manufacturers

Pharmacia And Upjohn Company Llc

CAS number

56420-45-2

UNII

3Z8479ZZ5X

State

solid

Affected organisms

Humans and other mammals

Indication of Epirubicin

For use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer.

Toxicity of Epirubicin

bone marrow aplasia, grade 4 mucositis, and gastrointestinal bleeding

RX24 Drugs Disclaimer: before buying a Epirubicin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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