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Price of Eptifibatide
Integrilin 75 mg/100 ml vial
* price without discount in nearest pharmacy. Price may vary.
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Eptifibatide volume of distribution
What is Eptifibatide
Synthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation.
Eptifibatide mechanism of action
Eptifibatide inhibits platelet aggregation by reversibly binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets, thus preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. Inhibition of platelet aggregation occurs in a dose- and concentration-dependent manner.
Dosage forms of Eptifibatide
Teva Parenteral Medicines, Inc.
Humans and other mammals
Indication of Eptifibatide
For treatment of myocardial infarction and acute coronary syndrome.
Toxicity of Eptifibatide
Eptifibatide was not lethal to rats, rabbits, or monkeys when administered by continuous intravenous infusion for 90 minutes at a total dose of 45 mg/kg (about 2 to 5 times the recommended maximum daily human dose on a body surface area basis)
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