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Price of Erythromycin
Emgel 2% topical gel
* price without discount in nearest pharmacy. Price may vary.
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Erythromycin volume of distribution
What is Erythromycin
Erythromycin is a macrolide antibiotic produced by Saccharopolyspora erythraea (formerly Streptomyces erythraeus). It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits; binding inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. Erythromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
Erythromycin mechanism of action
Erythromycin acts by penetrating the bacterial cell membrane and reversibly binding to the 50 S subunit of bacterial ribosomes or near the ldquo;P rdquo; or donor site so that binding of tRNA (transfer RNA) to the donor site is blocked. Translocation of peptides from the ldquo;A rdquo; or acceptor site to the ldquo;P rdquo; or donor site is prevented, and subsequent protein synthesis is inhibited. Erythromycin is effective only against actively dividing organisms. The exact mechanism by which erythmromycin reduces lesions of acne vulgaris is not fully known: however, the effect appears to be due in part to the antibacterial activity of the drug.
Dosage forms of Erythromycin
|Tablet (enteric-coated)||oral||250 mg|
Alti-erythromycin Tab 250mg USP
Altimed Pharma Inc.
Enteric bacteria and other eubacteria
Indication of Erythromycin
For use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to i Corynebacterium diphtheriae /i , in the treatment of infections due to i Corynebacterium minutissimum /i , intestinal amebiasis caused by i Entamoeba histolytica /i , acute pelvic inflammatory disease caused by i Neisseria gonorrhoeae /i , skin and soft tissue infections of mild to moderate severity caused by i Streptococcus pyogenes /i and i Staphylococcus aureus /i , primary syphilis caused by i Treponema pallidum /i , infections caused by i Chlamydia trachomatis /i , nongonococcal urethritis caused by i Ureaplasma urealyticum /i , and Legionnaires’ disease caused by i Legionella pneumophila /i .
Toxicity of Erythromycin
Symptoms of overdose include diarrhea, nausea, stomach cramps, and vomiting.
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