Save up -80% on Erythropoietin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Epogen
|$36.82||1 vial (1ml) 2000 units|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Epogen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Erythropoietin every time. What are you waiting for? Claim your prescription drug card now!
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Erythropoietin volume of distribution
Dose plasma erythropoietin concentrations were best described by a monoexponential disposition function with a mean (+/- s.d.) elimination half-life of 5.4 +/- 1.7 h. The volume of distribution was 70 +/- 5.2 ml kg-1 and the clearance was 10.1 +/- 3.5 ml h-1 kg-1 (n = 12).
|Solution for injection in a pre-filled syringe||Subcutaneous or intravenous use||1000 IU/0.5ml|
|Solution for injection in a pre-filled syringe||Subcutaneous or intravenous use||10000 IU/1.0ml|
|Solution for injection in a pre-filled syringe||Subcutaneous or intravenous use||2000 IU/1.0ml|
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Erythropoietin
Erythropoietin (as Epoetin alfa) is a 165-amino acid erythropoiesis-stimulating glycoprotein manufactured by recombinant DNA technology. It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin.
Erythropoietin mechanism of action
Binding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation.
Dosage forms of Erythropoietin
|Epogen||2000 units/ml||1 vial||$38|
|Epogen||3000 units/ml||1 vial||$55|
|Epogen||10000 units/ml||1 vial||$176|
|Epogen||20000 units/ml||1 vial||$345|
E.P.O. Epoetin alfa
Humans and other mammals
Indication of Erythropoietin
For treatment of anemia (from renal transplants or certain HIV treatment)
Toxicity of Erythropoietin
Ameliorative effect of Eprex when the drug was given in combination with GM and also when the drug was applied after GM–induced tubular damage, revealed the renoprotective potency of Eprex. Eprex is a promising drug to prevent or attenuate tubular damage induced by GM or other nephrotoxic agents which act through the same mechanisms as gentamicin.
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