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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Escitalopram

Lexapro 5 mg tablet

$3.4

tablet

* price without discount in nearest pharmacy. Price may vary.

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Escitalopram volume of distribution

* 12 L/kg

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What is Escitalopram

Escitalopram, the iS /i-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake. They have little to no effect on norepinephrine or dopamine reuptake and do not antagonize alpha;- or beta;-adrenergic, dopamine D sub2 /sub or histamine H sub1 /sub receptors. During acute use, SSRIs block serotonin reuptake and increase serotonin stimulation of somatodendritic 5-HT sub1A /sub and terminal autoreceptors. Chronic use leads to desensitization of somatodendritic 5-HT sub1A /sub and terminal autoreceptors. The overall clinical effect of increased mood and decreased anxiety is thought to be due to adaptive changes in neuronal function that leads to enhanced serotonergic neurotransmission. Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction and headache. Side effects generally occur within the first two weeks of therapy and are usually less severe and frequent than those observed with tricyclic antidepressants. Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD).

Escitalopram mechanism of action

The antidepressant, antiobsessive-compulsive, and antibulimic actions of escitalopram are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. Escitalopram blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT sub1A /sub autoreceptors. SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.

Dosage forms of Escitalopram

DrugDosageQuantityPrice
Escitalopram5mg100 Tablet$29.00
Escitalopram10mg100 Tablet$32.50
Escitalopram20mg84 Tablet$38.75
Lexapro5mg28 Tablet$39.90
Lexapro10mg28 Tablet$20.75
Lexapro20mg84 Blister Tablets$78.10
Prescription Generics

false

International Brands

Ach-escitalopram

Synonyms

(+)-Citalopram (S)-Citalopram

Manufacturers

Accord Healthcare Inc

CAS number

128196-01-0

UNII

4O4S742ANY

State

solid

Affected organisms

Humans and other mammals

Indication of Escitalopram

Labeled indications include major depressive disorder (MDD) and generalized anxiety disorder (GAD). Unlabeled indications include treatment of mild dementia-associated agitation in nonpsychotic patients.

Toxicity of Escitalopram

Signs of overdose include convulsions, coma, dizziness, hypotension, insomnia, nausea, vomiting, sinus tachycardia, somnolence, and ECG changes (including QT prolongation).

RX24 Drugs Disclaimer: before buying a Escitalopram on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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