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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Lunesta

$12.9530 tablets/3mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Lunesta coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Eszopiclone every time. What are you waiting for? Claim your prescription drug card now!

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Eszopiclone volume of distribution

Zopiclone is the first cyclopyrrolone hypnotic and is chemically unrelated to any existing drug. The authors studied the tissue distribution and postmortem redistribution of zopiclone in a fatal suicidal overdose. A 29-year-old female weighing 64 kg had cardiac blood ethanol 153 mg% and zopiclone blood concentrations in the range 0.9-2.0 ug/mL in 10 distinct sampling sites. After 40 hr at room temperature the range was 0.9-1.8 ug/mL in 15 samples. Portal venous blood and urine concentrations were 3.0 and 10.5 ug/mL, respectively.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Eszopiclone

Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic agent (viz., a sedative) used as a treatment for insomnia. Eszopiclone is the active stereoisomer of zopiclone, and belongs to the class of drugs known as cyclopyrrones. Its main selling point is that it is approved by the U.S. Food and Drug Administration for long-term use, unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia.

Eszopiclone mechanism of action

The mechanism of action of Eszopiclone is not completely understood. It is thought that Eszopiclone acts on the benzodiazepine receptors as an agonist and interacts with GABA-receptor complexes.

Dosage forms of Eszopiclone

Tabletoral1 mg/1
Tabletoral2 mg/1
Tabletoral3 mg/1

Prescription Generics


International Brands



(+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl-4-methylpiperazine-1-carboxylate


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Affected organisms

Humans and other mammals

Indication of Eszopiclone

For the treatment of insomnia

Toxicity of Eszopiclone

Side effects include viral infection, dry mouth, dizziness, hallucinations, infection, rash, and unpleasant taste, with this relationship clearest for unpleasant taste depending on doses.

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