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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Etacrynic acid

Edecrin 25 mg tablet

$3.19

tablet

* price without discount in nearest pharmacy. Price may vary.

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What is Etacrynic acid

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

Etacrynic acid mechanism of action

Ethacrynic acid inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. Diuretics also lower blood pressure initially by reducing plasma and extracellular fluid volume; cardiac output also decreases, explaining its antihypertensive action. Eventually, cardiac output returns to normal with an accompanying decrease in peripheral resistance. Its mode of action does not involve carbonic anhydrase inhibition.

Dosage forms of Etacrynic acid

FormRouteStrength
Tabletoral25 mg/1
Tabletoral25 mg
Tabletoral50 mg
Prescription Generics

false

International Brands

Edecrin

Synonyms

(2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid acide etacrynique

Manufacturers

Avera Mc Kennan Hospital

CAS number

58-54-8

UNII

M5DP350VZV

State

solid

Affected organisms

Humans and other mammals

Indication of Etacrynic acid

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Toxicity of Etacrynic acid

Overdosage may lead to excessive diuresis with electrolyte depletion.

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