Save up -80% on Ethambutol

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Myambutol

$53.8360 tablets/400 mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Ethambutol coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Ethambutol every time. What are you waiting for? Claim your prescription drug card now!

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Ethambutol volume of distribution

Ethambutol is widely distributed into most body tissues and fluids. Highest concentrations of the drug are found in erythrocytes, kidneys, lungs, and saliva; lower drug concentrations are found in ascitic fluid, pleural fluid, brain, and CSF. Peak intracellular concentrations of ethambutol in erythrocytes are about twice peak plasma concentrations and maintain this ratio for at least 24 hours after a single oral dose. In patients with meningitis, administration of an oral ethambutol hydrochloride dose of 25 mg/kg has produced peak CSF concentrations of the drug ranging from 0.15-2.0 ug/mL.

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2018 Statistics

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Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Ethambutol

An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)

Ethambutol mechanism of action

Ethambutol inhibits arabinosyl transferases which is involved in cell wall biosynthesis. By inhibiting this enzyme, the bacterial cell wall complex production is inhibited. This leads to an increase in cell wall permeability.

Dosage forms of Ethambutol

FormRouteStrength
Tabletoral100 mg/1
Tabletoral400 mg/1
Tablet, film coatedoral100 mg/1

Prescription Generics

true

International Brands

Ethambutol

Synonyms

(+)-2,2′-(ethylenediimino)di-1-butanol (+)-ethambutol

Manufacturers

Physicians Total Care, Inc.

CAS number

74-55-5

UNII

8G167061QZ

State

solid

Affected organisms

Humans and other mammals

Indication of Ethambutol

For use, as an adjunct, in the treatment of pulmonary tuberculosis.

Toxicity of Ethambutol

The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature. Other side effects that have been observed are pruritus, joint pain, gastrointestinal upset, abdominal pain, malaise, headache, dizziness, mental confusion, disorientation, and possible hallucinations.

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