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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ethopropazine

Parsitan 50 mg Tablet



* price without discount in nearest pharmacy. Price may vary.

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Ethopropazine volume of distribution

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What is Ethopropazine

Ethopropazine (also known as profenamine hydrochloride) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat parkinsonism. It is sold under the trade names Parsidol in the United States and Parsidan in Canada.

Ethopropazine mechanism of action

Ethopropazine’s antiparkinson action can be attributed to its anticholinergic properties. Ethopropazine partially blocks central (striatal) cholinergic receptors, thereby helping to balance cholinergic and dopaminergic activity in the basal ganglia; salivation may be decreased, and smooth muscle may be relaxed. Drug-induced extrapyramidal symptoms and those due to parkinsonism may be relieved, but tardive dyskinesia is not alleviated and may be aggravated by anticholinergic effects. Ethopropazine’s local anesthetic effect is due to its antagonism of the NMDA glutamate receptor. Glutamate is recognized as an important transmitter in nociceptive pathways, and the N-methyl-D-aspartate (NMDA) subtype of the glutamate receptor, in particular, has been implicated in the mediation of neuropathic pain. Excessive release of glutamate at NMDA receptors on dorsal horn neurons of the spinal cord results in hyperactivation and hypersensitivity of these receptors (perceived as hyperalgesia), thought to be an integral feature of neuropathic pain.

Dosage forms of Ethopropazine

Parsitan50mg100 Tablet$54.00
Prescription Generics


International Brands

Parsitan 50mg


10-(2-Diethylaminopropyl)phenothiazine 10-(2-(Diethylamino)-1-propyl)phenothiazine


Erfa Canada 2012 Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Ethopropazine

For use in the treatment of Parkinson‘s disease and also used to control severe reactions to certain medicines such as reserpine.

Toxicity of Ethopropazine

Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.

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