Save up -80% on Ethosuximide

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ethosuximide

Zarontin 250 mg capsule



* price without discount in nearest pharmacy. Price may vary.

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Ethosuximide volume of distribution

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What is Ethosuximide

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

Ethosuximide mechanism of action

Binds to T-type voltage sensitive calcium channels. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the “low-voltage activated (LVA)” group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Dosage forms of Ethosuximide

Zarontin250mg100 Capsule$79.00
Zarontin Syrup250mg/5mL200mL Syrup$32.00
Prescription Generics


International Brands



(+-)-2-Ethyl-2-methylsuccinimide ()-2-ethyl-2-methylsuccinimide


Versa Pharm Incorporated

CAS number






Affected organisms

Humans and other mammals

Indication of Ethosuximide

For the treatment of petit mal epilepsy.

Toxicity of Ethosuximide

Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression.

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