Save up -80% on Etomidate
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2018 Price of Etomidate
Etomidate 2 mg/ml vial
* price without discount in nearest pharmacy. Price may vary.
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Etomidate volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Etomidate
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Etomidate mechanism of action
Etomidate binds at a distinct binding site associated with a Cl sup – /sup ionopore at the GABA sub A /sub receptor, increasing the duration of time for which the Cl sup – /sup ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Dosage forms of Etomidate
|Injection, solution||intravenous||2 mg/mL|
(+)-Ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate (+)-ethyl 1-(-methylbenzyl)imidazole-5-carboxylate
Humans and other mammals
Indication of Etomidate
Used in the induction of general anesthesia.
Toxicity of Etomidate
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
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