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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Bydureon

$716.571 kit (4 pens) 2mg/pen
Price with discount in nearest pharmacy. Price may vary.

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Exenatide volume of distribution

The mean apparent volume of distribution after administration of a single subcutaneous dose is 28.3 L. The terminal half-life of the drug is 2.4 hours. Based on animal studies, the bioavailability of exenatide after subcutaneous injection has been estimated to be between 65% and 75%.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Exenatide

Exenatide, derived from a compound found in the saliva of the Gila monster, a large lizard native to the southwestern US, is a functional analog of Glucagon-Like Peptide-1 (GLP-1), a naturally occuring peptide.

Exenatide mechanism of action

Exenatide is a functional analog of the human incretin Glucagon-Like Peptide-1 (GLP-1). Incretins enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic actions following their release into the circulation from the gut. The GLP-1 system increases insulin secretion only in the presence of elevated plasma glucose levels, avoiding inappropriately high insulin levels during fasting. The drug also moderates peak serum glucagon levels during hyperglycemic periods following meals, but does not interfere with glucagon release in response to hypoglycemia. Secondary effects of drug administration reduces the rate of gastric emptying and decreases food intake, mitigating the potential severity of hyperglycemic events after meals.

Dosage forms of Exenatide

Injection, suspension, extended releasesubcutaneous2 mg/.65mL
Powder and solvent for prolonged-release suspension for injection in pre-filled penSubcutaneous use2 mg

Prescription Generics


International Brands

Bydureon, Byetta


AC 2993 AC-2993


Amylin Pharmaceuticals, LLC

CAS number






Affected organisms

Humans and other mammals

Indication of Exenatide

Indicated as adjunctive therapy to improve glycemic control in patients with Type 2 diabetes mellitus who are taking metformin, a sulfonylurea, or a combination of both, but have not achieved adequate glycemic control.

Toxicity of Exenatide

Effects of the overdoses included severe nausea, severe vomiting, and rapidly declining blood glucose concentrations.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Exenatide on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Bydureon?

Bydureon is an extended-release diabetes medicine that helps control blood sugar levels. This medicine helps your pancreas to produce insulin more effectively. Bydureon is a long-acting form of exenatide that is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes. This medicine is not for the treatment of type 1 diabetes.

You should not use Bydureon if you have severe kidney disease (or you are on dialysis), slow digestion, diabetic ketoacidosis, a personal or family history of thyroid cancer, or if you have a type of cancer called type 2 multiple endocrine neoplasia (MEN 2).

Stop using Bydureon and consult a doctor immediately if you have severe pain in your upper stomach, spreading to your back, with nausea, vomiting, and fast heart rate. These may be symptoms of pancreatitis.

Do not use Bydureon to treat type 1 diabetes, or if you are in a state of diabetic ketoacidosis (see your doctor for insulin treatment). Bydureon is an extended form of exenatide, administered as an injection once every seven days. The dose can be administered at any time of the day, with or without food. Follow your doctor’s instructions.