Save up -80% on Exenatide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Bydureon
|$716.57||1 kit (4 pens) 2mg/pen|
|price without discount in nearest pharmacy. Price may vary.|
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Exenatide volume of distribution
The mean apparent volume of distribution after administration of a single subcutaneous dose is 28.3 L. The terminal half-life of the drug is 2.4 hours. Based on animal studies, the bioavailability of exenatide after subcutaneous injection has been estimated to be between 65% and 75%.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Exenatide
Exenatide, derived from a compound found in the saliva of the Gila monster, a large lizard native to the southwestern US, is a functional analog of Glucagon-Like Peptide-1 (GLP-1), a naturally occuring peptide.
Exenatide mechanism of action
Exenatide is a functional analog of the human incretin Glucagon-Like Peptide-1 (GLP-1). Incretins enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic actions following their release into the circulation from the gut. The GLP-1 system increases insulin secretion only in the presence of elevated plasma glucose levels, avoiding inappropriately high insulin levels during fasting. The drug also moderates peak serum glucagon levels during hyperglycemic periods following meals, but does not interfere with glucagon release in response to hypoglycemia. Secondary effects of drug administration reduces the rate of gastric emptying and decreases food intake, mitigating the potential severity of hyperglycemic events after meals.
Dosage forms of Exenatide
|Injection, suspension, extended release||subcutaneous||2 mg/.65mL|
|Powder and solvent for prolonged-release suspension for injection in pre-filled pen||Subcutaneous use||2 mg|
AC 2993 AC-2993
Amylin Pharmaceuticals, LLC
Humans and other mammals
Indication of Exenatide
Indicated as adjunctive therapy to improve glycemic control in patients with Type 2 diabetes mellitus who are taking metformin, a sulfonylurea, or a combination of both, but have not achieved adequate glycemic control.
Toxicity of Exenatide
Effects of the overdoses included severe nausea, severe vomiting, and rapidly declining blood glucose concentrations.
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What is Bydureon?
Bydureon is an extended-release diabetes medicine that helps control blood sugar levels. This medicine helps your pancreas to produce insulin more effectively. Bydureon is a long-acting form of exenatide that is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes. This medicine is not for the treatment of type 1 diabetes.
You should not use Bydureon if you have severe kidney disease (or you are on dialysis), slow digestion, diabetic ketoacidosis, a personal or family history of thyroid cancer, or if you have a type of cancer called type 2 multiple endocrine neoplasia (MEN 2).
Stop using Bydureon and consult a doctor immediately if you have severe pain in your upper stomach, spreading to your back, with nausea, vomiting, and fast heart rate. These may be symptoms of pancreatitis.
Do not use Bydureon to treat type 1 diabetes, or if you are in a state of diabetic ketoacidosis (see your doctor for insulin treatment). Bydureon is an extended form of exenatide, administered as an injection once every seven days. The dose can be administered at any time of the day, with or without food. Follow your doctor’s instructions.