Save up -80% on Febuxostat

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Febuxostat

$

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Febuxostat volume of distribution

The mean apparent steady state volume of distribution (Vss/F) of febuxostat was approximately 50 L (CV ~40%)

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What is Febuxostat

Febuxostat is a xanathine oxidase (XO) inhibitor indicated in patients with gout suffering from hyperuricemia and is used in its chronic management. Febuxostat is not recommended for the treatment of asymptomatic hyperuricemia. Febuxostat is marketed under the trade name Uloric by Takeda Pharmaceuticals America, Inc., and was approved by the FDA in February 2009.

Febuxostat mechanism of action

Febuxostat, a xanthine oxidase inhibitor, achieves its therapeutic effect by decreasing serum uric acid. Febuxostat is not expected to inhibit other enzymes involved in purine and pyrimidine synthesis and metabolism at therapeutic concentrations.

Dosage forms of Febuxostat

FormRouteStrength
Film-coated tabletOral use120 mg
Film-coated tabletOral use80 mg
Tablet, film coatedoral40 mg/1
Prescription Generics

true

International Brands

Febuxostat

Synonyms

2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid Febuxostat

Manufacturers

Ranbaxy Pharmaceuticals Inc.

CAS number

144060-53-7

UNII

101V0R1N2E

State

solid

Affected organisms

Humans and other mammals

Indication of Febuxostat

For the treatment of hyperuricemia in patients with gout.

Toxicity of Febuxostat

The FDA adverse event reporting system database, AERS, indicated potential signals of febuxostat-associated cardiovascular thromboembolic events. AERS is not capable of establishing the causal link and detecting the true frequency of an adverse event associated with a drug. The positive IC value found in this study merits continued surveillance and assessment of cardiovascular thromboembolic events associated with Febuxostat.

RX24 Drugs Disclaimer: before buying a Febuxostat on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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