Save up -80% on Felbamate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Felbatol
|price without discount in nearest pharmacy. Price may vary.|
We offer free Felbamate coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Felbamate every time. What are you waiting for? Claim your prescription drug card now!
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Felbamate volume of distribution
The apparent volume of distribution was 756±82 mL/kg after a 1200 mg dose.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Felbamate
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak inhibitory effect on GABA receptor binding sites.
Felbamate mechanism of action
The mechanism by which felbamate exerts its anticonvulsant activity is unknown, but in animal test systems designed to detect anticonvulsant activity, felbamate has properties in common with other marketed anticonvulsants. i In vitro /i receptor binding studies suggest that felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex. Antagonism of the NMDA receptor glycine binding site may block the effects of the excitatory amino acids and suppress seizure activity. Animal studies indicate that felbamate may increase the seizure threshold and may decrease seizure spread. It is also indicated that felbamate has weak inhibitory effects on GABA-receptor binding, benzodiazepine receptor binding.
Dosage forms of Felbamate
2-Phenyl-1,3-propanediol dicarbamate Carbamic acid 2-phenyltrimethylene ester
Carilion Materials Management
Humans and other mammals
Indication of Felbamate
For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.
Toxicity of Felbamate
LD sub 50 /sub =5000 mg/kg (Orally in rats)
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