Save up -80% on Fenoldopam

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Fenoldopam

Corlopam 10 mg/ml ampul

$81.9

ml

* price without discount in nearest pharmacy. Price may vary.

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Fenoldopam volume of distribution

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What is Fenoldopam

A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.

Fenoldopam mechanism of action

Fenoldopam is a rapid-acting vasodilator. It is an agonist for Dsub1/sub-like dopamine receptors and binds with moderate affinity toalpha;sub2/sub-adrenoceptors. It has no significant affinity for Dsub2/sub-like receptors,alpha;sub1/sub andbeta;-adrenoceptors, 5subHT1/sub and 5subHT2/sub receptors, or muscarinic receptors. Fenoldopam is a racemic mixture with the R-isomer responsible for the biological activity. The R-isomer has approximately 250-fold higher affinity for Dsub1/sub-like receptors than does the S-isomer. In non-clinical studies, fenoldopam had no agonist effect on presynaptic Dsub2/sub-like dopamine receptors, oralpha; orbeta; -adrenoceptors, nor did it affect angiotensin-converting enzyme activity. Fenoldopam may increase norepinephrine plasma concentration.

Dosage forms of Fenoldopam

FormRouteStrength
Injection, solutionintravenous10 mg/mL
Prescription Generics

false

International Brands

Corlopam

Synonyms

Fenoldopam Fenoldopam

Manufacturers

Hospira, Inc.

CAS number

67227-56-9

UNII

INU8H2KAWG

State

solid

Affected organisms

Humans and other mammals

Indication of Fenoldopam

For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.

Toxicity of Fenoldopam

The most likely reaction of overdose would be excessive hypotension which should be treated with drug discontinuation and appropriate supportive measures.

RX24 Drugs Disclaimer: before buying a Fenoldopam on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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