Save up -80% on Fingolimod
Note: this is a drug discount program, not an insurance plan.
2018 Price of Fingolimod
* price without discount in nearest pharmacy. Price may vary.
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Fingolimod volume of distribution
about 1200 260 L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Fingolimod mechanism of action
Fingolimod is metabolized by sphingosine kinase to the active metabolite, fingolimod-phosphate. Fingolimod-phosphate is a sphingosine 1-phosphate receptor modulator, and binds with high affinity to sphingosine 1-phosphate receptors 1, 3, 4, and 5. Fingolimod-phosphate blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood. The mechanism by which fingolimod exerts therapeutic effects in multiple sclerosis is unknown, but may involve reduction of lymphocyte migration into the central nervous system.
Dosage forms of Fingolimod
|Capsule, hard||Oral use||0.5 mg|
Novartis Pharmaceuticals Corporation
Humans and other mammals
Indication of Fingolimod
Fingolimod is a sphingosine 1-phosphate receptor modulator indicated for the treatment of patients with relapsing forms of multiple sclerosis to reduce the frequency of clinical exacerbations and to delay the accumulation of physical disability.
Toxicity of Fingolimod
Bradyarrhythmia and Atrioventricular Blocks Risk of infections Macular Edema Respiratory Effects Hepatic Effects Fetal Risk Blood Pressure Effects Immune System Effects Following Fingolimod Discontinuation
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