Save up -80% on Flunisolide
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Price of Flunisolide
Nasarel 29 mcg-0.025% spray
* price without discount in nearest pharmacy. Price may vary.
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Flunisolide volume of distribution
What is Flunisolide
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid often prescribed as treatment for allergic rhinitis. The principle mechanism of action of flunisolide is to activate glucocorticoid receptors. It also has anti-inflammatory action.
Flunisolide mechanism of action
Flunisolide is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Flunisolide binds to plasma transcortin, and it becomes active when it is not bound to transcortin.
Dosage forms of Flunisolide
|Aerosol, metered||respiratory (inhalation)||80 ug/1|
|Metered-dose pump||nasal||0.25 mg|
|Metered-dose aerosol||inhalation||250 mcg|
Acton Pharmaceuticals, Inc.
Humans and other mammals
Indication of Flunisolide
For the maintenance treatment of asthma as a prophylactic therapy.
Toxicity of Flunisolide
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