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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Prolixin

$22.6230 tablets/5 mg
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Fluphenazine volume of distribution

After intravenous FLU-D, the pharmacokinetics of the prodrug (mean +/- SD) were as follows: Clearance (CL) 42.9 +/- 6.3 L/h; terminal half-life (t1/2) 3.5 +/- 0.8 h; volume of distribution (Vd) 216 +/- 61 L. The fractional availability of FLU was 1.0 +/- 0.2. After intravenous FLU, the volume of distribution of FLU (51 +/- 17.8 L) was some 4 fold less than that of the prodrug.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

Fluphenazine mechanism of action

Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

Dosage forms of Fluphenazine

Tabletoral2.5 mg
Injectionintramuscular; subcutaneous25 mg/mL
Injection, solutionintramuscular; subcutaneous25 mg/mL

Prescription Generics


International Brands

Apo Fluphenazine Tab 2.5mg


1-(2-Hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine 10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine


Apotex Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Fluphenazine

For management of manifestations of psychotic disorders.

Toxicity of Fluphenazine

Fluphenazine administration to horses may result in characteristic clinical signs of toxicity. Fluphenazine is a highly potent phenothiazine neuroleptic that is widely used in human medicine for a variety of psychological disturbances.

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