Save up -80% on Fluvastatin

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Fluvastatin

Lescol 40 mg Capsule

$1.35

capsule

* price without discount in nearest pharmacy. Price may vary.

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Fluvastatin volume of distribution

* 0.35 L/kg

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What is Fluvastatin

Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.

Fluvastatin mechanism of action

Fluvastatin selectively and competitively inhibits the hepatic enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate, the rate-limiting step in cholesterol biosynthesis. Inhibition results in a decrease in hepatic cholesterol levels which stimulates the synthesis of LDL receptors and increases hepatic uptake of LDL cholesterol. The end result is decreased levels of plasma total and LDL cholesterol.

Dosage forms of Fluvastatin

DrugDosageQuantityPrice
Lescol XL80mg84 ER Tablet$104.00
Fluvastatin20mg84 Capsule$78.00
Fluvastatin40mg84 Capsule$88.00
Prescription Generics

true

International Brands

Fluvastatin

Synonyms

Manufacturers

Teva Pharmaceuticals USA Inc

CAS number

93957-54-1

UNII

4L066368AS

State

solid

Affected organisms

Humans and other mammals

Indication of Fluvastatin

To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.

Toxicity of Fluvastatin

Generally well-tolerated. May cause gastrointestinal upset (diarrhea, nausea, constipation, gas, abdominal pain), myotoxicity (mypothy, myositis, rhabdomyolysis), and hepatotoxicity.

RX24 Drugs Disclaimer: before buying a Fluvastatin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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