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Price of Fluvoxamine
Luvox 100 mg Tablet
* price without discount in nearest pharmacy. Price may vary.
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Fluvoxamine volume of distribution
* 25 L/kg
What is Fluvoxamine
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.
Fluvoxamine mechanism of action
The exact mechanism of action of fluvoxamine has not been fully determined, but appears to be linked to its inhibition of CNS neuronal uptake of serotonin. Fluvoxamine blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT sub 1A /sub autoreceptors. In-vitro studies suggest that fluvoxamine is more potent than clomipramine, fluoxetine, and desipramine as a serotonin-reuptake inhibitor. Studies have also demonstrated that fluvoxamine has virtually no affinity for . sub 1 /sub – or . sub 2 /sub -adrenergic, .-adrenergic, muscarinic, dopamine D sub 2 /sub , histamine H sub 1 /sub , GABA-benzodiazepine, opiate, 5-HT sub 1 /sub , or 5-HT sub 2 /sub receptors.
Dosage forms of Fluvoxamine
|Capsule, extended release||oral||100 mg/1|
Actavis Pharma Company
Humans and other mammals
Indication of Fluvoxamine
For management of depression and for Obsessive Compulsive Disorder (OCD). Has also been used in the management of bulimia nervosa.
Toxicity of Fluvoxamine
Side effects include anorexia, constipation, dry mouth, headache, nausea, nervousness, skin rash, sleep problems, somnolence, liver toxicity, mania, increase urination, seizures, sweating increase, tremors, or Tourette’s syndrome.
Disclaimer: before buying a Fluvoxamine on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.