Save up -80% on Fosamprenavir
Note: this is a drug discount program, not an insurance plan.
2018 Price of Fosamprenavir
Lexiva 700 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Fosamprenavir volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Fosamprenavir mechanism of action
Fosamprenavir is a prodrug that is rapidly hydrolyzed to amprenavir by cellular phosphatases in the gut epithelium as it is absorbed. Amprenavir is an inhibitor of HIV-1 protease. During HIV replication, HIV protease cleaves viral polypeptide products of the Gag and Gag-Pol genes to form structural proteins of the virion core and essential viral enzymes. Amprenavir interferes with this process by binding to the active site of HIV-1 protease, thereby preventing the processing of viral Gag and Gag-Pol polyprotein precursors, resulting in the formation of immature non-infectious viral particles.
Dosage forms of Fosamprenavir
|Tablet, film coated||oral||700 mg/1|
|Film-coated tablets||Oral use||700 mg|
Human Immunodeficiency Virus
Indication of Fosamprenavir
Indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus (HIV-1) infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission. The use of fosamprenavir is pending revision due to a potential association between the drug and myocardial infarction and dyslipidemia in HIV infected adults.
Toxicity of Fosamprenavir
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