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Price of Foscarnet
Sodium phosphonoformate powder
* price without discount in nearest pharmacy. Price may vary.
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Foscarnet volume of distribution
What is Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV. (PubChem)
Foscarnet mechanism of action
Foscarnet exerts its antiviral activity by a selective inhibition at the pyrophosphate binding site on virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases.
Dosage forms of Foscarnet
|Injection, solution||intravenous||24 mg/mL|
Human Herpes Virus
Indication of Foscarnet
For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.
Toxicity of Foscarnet
Oral, rat LD sub50 /sub: 2,000 mg/kg. Signs of overdose include renal impairment.
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