Save up -80% on Framycetin

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Framycetin

Neomycin 500 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Framycetin volume of distribution

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What is Framycetin

A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)

Framycetin mechanism of action

Framycetin binds to specific 30S-subunit proteins and 16S rRNA, four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.

Dosage forms of Framycetin

Form Route Strength
Solution ophthalmic; otic
Dressing topical 1 %
Ointment ophthalmic; otic
Prescription Generics


International Brands

Sandoz Opticort


Fradiomycin B Framicetina


Sandoz Canada Incorporated

CAS number






Affected organisms

Enteric bacteria and other eubacteria

Indication of Framycetin

For the treatment of bacterial blepharitis, bacterial bonjunctivitis, corneal injuries, corneal ulcers and meibomianitis. For the prophylaxis of ocular infections following foreign body removal

Toxicity of Framycetin

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