Save up -80% on Frovatriptan
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Frova
|$165.28||1 dose pack (9 tablets) 2.5mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Frova coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Frovatriptan every time. What are you waiting for? Claim your prescription drug card now!
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Frovatriptan volume of distribution
Reversible binding to blood cells at equilibrium is approximately 60%, resulting in a blood:plasma ratio of about 2:1 in both males and females. The mean steady state volume of distribution of frovatriptan following intravenous administration of 0.8 mg is 4.2 L/kg in males and 3.0 L/kg in females.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Frovatriptan
Frovatriptan (Frova) is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.(1) Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. It is available as 2.5 mg tablets. Frovatriptan has mean terminal elimination half-life of approximately 26 hours, which is substantially longer than other triptans. Frovatriptan is available only by prescription in the United States, where a secondary New Drug Approval (sNDA) was filed in July 2006(2) and which is currently pending.(3) The FDA anticipates completing its review of this application on or before the current PDUFA (Prescription Drug User Fee Act) review date of August 19, 2007. If the sNDA is approved, Frova will be the only medication indicated in the U.S. for the short-term prevention of menstrual migraine (MM).
Frovatriptan mechanism of action
Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT sub 1D /sub receptors, which serves to inhibit both dural vasodilation and inflammation; (2) direct inhibition of trigeminal nuclei cell excitability via 5-HT sub 1B/1D /sub receptor agonism in the brainstem and (3) vasoconstriction of meningeal, dural, cerebral or pial vessels as a result of vascular 5-HT sub 1B /sub receptor agonism.
Dosage forms of Frovatriptan
|Tablet, film coated||oral||2.5 mg/1|
Allergo filmtabletten Frovatriptan succinate
Lake Erie Medical DBA Quality Care Products LLC
Humans and other mammals
Indication of Frovatriptan
For the acute treatment of migraine attacks with or without aura in adults.
Toxicity of Frovatriptan
There is no direct experience of any patient taking an overdose of Frovatriptan. The maximum single dose of frovatriptan given to male and female patients with migraine was 40 mg (16 times the clinical dose) and the maximum single dose given to healthy male subjects was 100 mg (40 times the clinical dose) without significant adverse events.
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