Save up -80% on Fulvestrant

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Fulvestrant

Faslodex 125 mg/2.5 ml syringe

$240.83

ml

* price without discount in nearest pharmacy. Price may vary.

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Fulvestrant volume of distribution

* 3 to 5 L/kg

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What is Fulvestrant

Fulvestrant is a drug treatment of hormone receptor-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

Fulvestrant mechanism of action

Fulvestrant competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. First, fulvestrant binds to the receptors and downregulates them so that estrogen is no longer able to bind to these receptors. Second, fulvestrant degrades the estrogen receptors to which it is bound. Both of these mechanisms inhibit the growth of tamoxifen-resistant as well as estrogen-sensitive human breast cancer cell lines.

Dosage forms of Fulvestrant

FormRouteStrength
Injectionintramuscular50 mg/mL
Solutionintramuscular50 mg
Solution for injectionIntramuscular use250 mg/5ml
Prescription Generics

false

International Brands

Faslodex

Synonyms

ICI 182,780

Manufacturers

Astra Zeneca Pharmaceuticals Lp

CAS number

129453-61-8

UNII

22X328QOC4

State

solid

Affected organisms

Humans and other mammals

Indication of Fulvestrant

For the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy.

Toxicity of Fulvestrant

There is no clinical experience with overdosage in humans.

RX24 Drugs Disclaimer: before buying a Fulvestrant on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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