Save up -80% on Fulvestrant
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Faslodex
|$1,970.29||2 syringes (5ml) 50mg/ml|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Fulvestrant coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Fulvestrant every time. What are you waiting for? Claim your prescription drug card now!
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Fulvestrant volume of distribution
Fulvestrant was subject to extensive and rapid distribution, with estimates of the volume of distribution (Vss) at the steady state ranging from 3.0 to 5.3 l kg−1.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Fulvestrant
Fulvestrant is a drug treatment of hormone receptor-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
Fulvestrant mechanism of action
Fulvestrant competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. First, fulvestrant binds to the receptors and downregulates them so that estrogen is no longer able to bind to these receptors. Second, fulvestrant degrades the estrogen receptors to which it is bound. Both of these mechanisms inhibit the growth of tamoxifen-resistant as well as estrogen-sensitive human breast cancer cell lines.
Dosage forms of Fulvestrant
|Solution for injection||Intramuscular use||250 mg/5ml|
Astra Zeneca Pharmaceuticals Lp
Humans and other mammals
Indication of Fulvestrant
For the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy.
Toxicity of Fulvestrant
There is no clinical experience with overdosage in humans.
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