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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Furosemide

Lasix 80 mg tablet

$1.0

tablet

* price without discount in nearest pharmacy. Price may vary.

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Furosemide volume of distribution

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What is Furosemide

A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency.

Furosemide mechanism of action

Furosemide, a loop diuretic, inhibits water reabsorption in the nephron by blocking the sodium-potassium-chloride cotransporter (NKCC2) in the thick ascending limb of the loop of Henle. This is achieved through competitive inhibition at the chloride binding site on the cotransporter, thus preventing the transport of sodium from the lumen of the loop of Henle into the basolateral interstitium. Consequently, the lumen becomes more hypertonic while the interstitium becomes less hypertonic, which in turn diminishes the osmotic gradient for water reabsorption throughout the nephron. Because the thick ascending limb is responsible for 25% of sodium reabsorption in the nephron, furosemide is a very potent diuretic.

Dosage forms of Furosemide

DrugDosageQuantityPrice
Furosemide20mg100 Scored Tablet$35.00
Furosemide40mg28 Tablet$18.00
Furosemide40mg84 Tablet$36.00
Furosemide80mg100 Scored Tablet$45.00
Lasix40mg90 Tablet$21.40
Lasix10mg/mL120mL Oral solution$62.50
Prescription Generics

true

International Brands

Apo Furosemide Tab 20mg

Synonyms

2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid

Manufacturers

Apotex Inc

CAS number

54-31-9

UNII

7LXU5N7ZO5

State

solid

Affected organisms

Humans and other mammals

Indication of Furosemide

For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.

Toxicity of Furosemide

Profound diuresis may cause fluid and electrolyte depletion. Excessive dehydration and potassium depletion may occur. Excessive diuresis may cause rapid weight loss, orthostatic hypotension or acute hypotensive episodes. May also cause tinnitus, reversible or permanent hearing loss or reversible deafness.

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