Save up -80% on Gemifloxacin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Factive
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Gemifloxacin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Gemifloxacin every time. What are you waiting for? Claim your prescription drug card now!
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Gemifloxacin volume of distribution
* 1.66 to 12.12 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Gemifloxacin
Gemifloxacin is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.
Gemifloxacin mechanism of action
The bactericidal action of gemifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.
Dosage forms of Gemifloxacin
|Gemifloxacin Mesylate||320mg||50 Tablet||$66.00|
|Gemifloxacin Mesylate||320mg||100 Tablet||$122.00|
Factiv Gemifloxacin mesilate
Oscient Pharmaceuticals Corporation
Enteric bacteria and other eubacteria
Indication of Gemifloxacin
For the treatment of bacterial infection caused by susceptible strains such as iS. pneumoniae /i, iH. influenzae /i, iH. parainfluenzae /i, or iM. catarrhalis /i, iS. pneumoniae /i (including multi-drug resistant strains (MDRSP)), iM. pneumoniae /i, iC. pneumoniae /i, or iK. pneumoniae /i.
Toxicity of Gemifloxacin
Gemifloxacin (jem” i flox’ a sin), like other fluoroquinolones, is associated with a low rate (1% to 7%) of serum enzyme elevations during therapy, although this rate may be slightly higher than occurs with placebo or comparative agents. These abnormalities are generally mild, asymptomatic and transient, resolving even with continuation of therapy. Too few cases of hepatotoxicity due to gemifloxacin have been reported to provide a reliable description of its clinical features and course. However, the liver injury due to the fluoroquinolones appears to be a class effect, and gemifloxacin injury appears to share these characteristics. It is a far less common cause of liver injury than ciprofloxacin, levofloxacin or moxifloxacin, but cases have been reported. In general, fluoroquinone hepatotoxicity is marked by a short time to onset (a few days to 3 weeks); often presenting abruptly with marked nausea, fatigue, abdominal pain and jaundice. The pattern of serum enzyme elevations can be either hepatocellular or holestatic, and cases with the shorter times to onset are usually more hepatocellular with markedly elevated ALT levels, and occasionally, with rapid worsening of prothrombin time and signs of hepatic failure. The onset of illness may occur a few days after the medication is stopped. Many (but not all) cases have had allergic manifestations with fever, rash and eosinophilia. Autoantibodies are usually not present.
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