Save up -80% on Glimepiride
Note: this is a drug discount program, not an insurance plan.
2018 Price of Glimepiride
Amaryl 2 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Glimepiride mechanism of action
The mechanism of action of glimepiride in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Glimepiride likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin.
Dosage forms of Glimepiride
Sanofi Aventis Canada Inc
Humans and other mammals
Indication of Glimepiride
For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
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