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Price of Glucagon recombinant
Glucagen 1 mg vial
* price without discount in nearest pharmacy. Price may vary.
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Glucagon recombinant volume of distribution
* 0.25 L/kg
What is Glucagon recombinant
29 residue peptide hormone. Glucagon is synthesized in a special non- pathogenic laboratory strain of Escherichia coli bacteria that has been genetically altered by the addition of the gene for glucagons
Glucagon recombinant mechanism of action
Glucagon binds the glucagon receptor, a G protein-coupled receptor located in the plasma membrane, which then initiates a dual signaling pathway using both adenylate cyclase activation and increased intracellular calcium. Adenylate cyclase manufactures cAMP (cyclic AMP), which activates protein kinase A (cAMP-dependent protein kinase). This enzyme, in turn, activates phosphorylase kinase, which, in turn, phosphorylates glycogen phosphorylase, converting into the active form called phosphorylase A. Phosphorylase A is the enzyme responsible for the release of glucose-1-phosphate from glycogen polymers. This yields glucose molecules to be released into the blood. Glucagon receptors are found in the liver, kidney, brain and pancreatic islet cells. The glucagon mediated signals lead to an increase in insulin excretion
Dosage forms of Glucagon recombinant
|Injection, powder, for solution||intramuscular; intravenous; subcutaneous||1 mg/mL|
|Kit; powder for solution||intramuscular||1 mg|
Glucagon (recombinant dna origin)
Boehringer Ingelheim Pharmaceuticals, Inc.
Humans and other mammals
Indication of Glucagon recombinant
For treatment of severe hypoglycemia, also used in gastrointestinal imaging
Toxicity of Glucagon recombinant
Disclaimer: before buying a Glucagon recombinant on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.