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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Glycopyrronium

Robinul 0.2 mg/ml vial

$1.26

ml

* price without discount in nearest pharmacy. Price may vary.

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Glycopyrronium volume of distribution

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What is Glycopyrronium

Glycopyrronium (as the bromide salt glycopyrrolate) is a synthetic anticholinergic agent with a quaternary ammonium structure. A muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. In October 2015, glycopyrrolate was approved by the FDA for use as a standalone treatment for Chronic obstructive pulmonary disease (COPD), as Seebri Neohaler.

Glycopyrronium mechanism of action

Glycopyrrolate binds competitively to the muscarinic acetylcholine receptor. Like other anticholinergic (antimuscarinic) agents, it inhibits the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, exocrine glands and, to a limited degree, in the autonomic ganglia. Thus, it diminishes the volume and free acidity of gastric secretions and controls excessive pharyngeal, tracheal, and bronchial secretions.

Dosage forms of Glycopyrronium

FormRouteStrength
Aerosol, meteredrespiratory (inhalation)
Liquidoral1 mg/5mL
Inhalation powder, hard capsuleInhalation use44 micrograms
Prescription Generics

false

International Brands

Bevespi Aerosphere

Synonyms

Glycopyrrolate cation Glycopyrrolate ion

Manufacturers

Astra Zeneca Pharmaceuticals Lp

CAS number

740028-90-4

UNII

A14FB57V1D

State

solid

Affected organisms

Humans and other mammals

Indication of Glycopyrronium

For use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Also used to treat chronic obstructive pulmonary disease (COPD).

Toxicity of Glycopyrronium

Side effects include dry mouth, difficult urinating, heachaches, diarrhea and constipation. The medication also induces drowsiness or blurred vision. LD sub 50 /sub =709 mg/kg (rat, oral).

RX24 Drugs Disclaimer: before buying a Glycopyrronium on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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