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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Mucinex

$8.0120 tablets/600 mg
Price with discount in nearest pharmacy. Price may vary.

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Guaifenesin volume of distribution

Arterial blood samples were collected before and at 5 and 15 min intervals during recumbency for analysis of pH, CO2, and O2. ANOVA was used to evaluate dynamic data, while t-tests were used for kinetic values. Respiratory rate was decreased significantly during recumbency, but no other significant changes from baseline occurred. The mean (+/- SD) recumbency dose of guaifenesin was 131 mg/kg (27) for donkeys and 211 mg/kg (8) for horses. Recovery time to sternal (min) was 15 (SD, 11) for donkeys and 34 (SD, 1.4) for horses. Time to standing was 32 min for donkeys and 36 min for horses. Calculation of AUC (area under the concentration-time curve) microgram/mL) (dose-dependent variable) was 231 (SD, 33) for donkeys and 688 (SD, 110) for horses. The clearance (CL) (mL/ was 546 (SD, 73) for donkeys, which was significantly different from 313 (SD, 62) for horses. Mean residence time (MRT) (hr) was 1.2 (SD, 0.1) for donkeys and 2.6 (SD, 0.5) for horses. Volume of distribution Vd(area) (mL/kg) was 678 (SD, 92) for donkeys and 794 (SD, 25) for horses. At the rate of administration used in this study, donkeys required less guaifenesin than horses to produce recumbency, but cleared it more rapidly.

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What is Guaifenesin

An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Guaifenesin mechanism of action

Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mixture. Cough may be provoked. This combination may flush tenacious, congealed mucopurulent material from obstructed small airways and lead to a temporary improvement in dyspnea or the work of breathing.

Dosage forms of Guaifenesin

Mucinex600mg20 Extended Release 12Hour Tablet$43.00
Robitussin DM Extra Strength200mg100mL Syrup$26.00
Robitussin DM Cough Control100/15mg100mL Syrup$26.00

Prescription Generics


International Brands

7 Select Mucus Relief


Glyceryl guaiacolate guaiphenesin


7 Eleven

CAS number






Affected organisms

Humans and other mammals

Indication of Guaifenesin

Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.

Toxicity of Guaifenesin

LDsub50/sub 1510 mg/kg (rat, oral)

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Guaifenesin on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Mucinex?

Mucinex is an expectorant. This helps to loosen the congestion in the chest and throat, which makes it easier for gushing through the mouth. Mucinex is used to reduce chest congestion caused by a cold, infection, or allergies.

Follow all directions on label and package. Tell each of your health care providers about all your medical conditions, allergies, and all medications you use. You should not use Mucinex if you are allergic to Guaifenesin. Ask a doctor or pharmacist if you can use Mucinex if you have other medical conditions.

It is unknown whether Mucinex harms the unborn child. Ask a doctor before using this medicine if you are pregnant. It is not known whether guaifenesin passes into breast milk or can harm a feeding baby. Ask a doctor before using this medicine if you are breastfeeding. Do not give Mucinex to a child without medical advice.