Save up -80% on Guanfacine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tenex
|$10.18||30 tablets/1 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Guanfacine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Guanfacine every time. What are you waiting for? Claim your prescription drug card now!
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Guanfacine volume of distribution
* 6.3 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Guanfacine
A centrally acting antihypertensive agent. The drug lowers both systolic and diastolic blood pressure by activating the central nervous system alpha-2 adrenoreceptors, which results in reduced sympathetic outflow leading to reduced vascular tone. Its adverse reactions include dry mouth, sedation, and constipation.
Guanfacine mechanism of action
Guanfacine selectively stimulates central alpha(2)-adrenergic receptors, resulting in inhibition of sympathetic vasomotor centers, which contributes predominantly to the hypotensive effects of the drug. Central effects of guanfacine lead to reduced peripheral sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This results in a decrease in peripheral vascular resistance and a reduction in heart rate. The stimulation of peripheral alpha(2)-adrenergic receptors may also contribute to hypotensive effects.
Dosage forms of Guanfacine
|Tablet, extended release||oral||1 mg/1|
Epic Pharma, LLC
Humans and other mammals
Indication of Guanfacine
For use alone or in combination with other classes of antihypertensive agents in the management of hypertension. Has also been used for the treatment of attention deficit hyperactivity disorder (ADHD) in pediatric patients.
Toxicity of Guanfacine
Symptoms of overdose include drowsiness, lethargy, bradycardia and hypotension. LD sub 50 /sub =165mg/kg (orally in mice)
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