Save up -80% on Ibandronate

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Boniva

$575.511 dose pack (3 tablets) 150mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Boniva coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Ibandronate every time. What are you waiting for? Claim your prescription drug card now!

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Ibandronate volume of distribution

90 L. Poorly absorbed (mean bioavailability following a 2.5 mg oral dose is about 0.6% compared to intravenous dosing). Absorption is impaired by any kind of food or drink other than plain water.

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Ibandronate

Ibandronate is a nitrogen-containing bisphosphonate in the same class as alendronate and risedronate. Ibandronate inhibits osteoclast-mediated bone resorption. All of the bisphosphonates prevent the breakdown of bone by bone cells called osteoclasts. In persons who are at high risk for osteoporosis, bisphosphonates not only result in increased amounts of bone and bone strength, they also reduce the risk of hip fractures and other bone fractures.

Ibandronate mechanism of action

The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting farnesyl pyrophosphate (FPP) synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Dosage forms of Ibandronate

DrugDosageQuantityPrice
Ibandronate Sodium3mg/3ml1 Injection$76.00
Ibandronate Sodium3mg/3ml10 Injection$541.40
Ibandronate Sodium150mg3 Tablet$26.00
Boniva Injection3mg/3ml1 Injection$498.40
Boniva150mg3 Tablet$127.50

Prescription Generics

false

International Brands

Bondronat

Synonyms

Bondronat Ibandronic Acid

Manufacturers

Hoffmann La Roche Limited

CAS number

114084-78-5

UNII

UMD7G2653W

State

solid

Affected organisms

Humans and other mammals

Indication of Ibandronate

For the treatment and prevention of osteoporosis in postmenopausal women.

Toxicity of Ibandronate

LD sub50 /sub = 811 mg/kg (rat, oral), side effects include bronchitis, pneumonia and urinary tract infections.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Ibandronate on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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