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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ibritumomab tiuxetan

Zevalin in-111 kit

$4200.0

kit

* price without discount in nearest pharmacy. Price may vary.

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Ibritumomab tiuxetan volume of distribution

Binding observed on lymphoid cells of the bone marrow, lymph node, thymus, red and white pulp of the spleen, lymphoid follicles of the tonsil, and lymphoid nodules of other organs (e.g., large and small intestines)

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What is Ibritumomab tiuxetan

Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.

Ibritumomab tiuxetan mechanism of action

The Fab segment of the antibody targets the CD20 epitope on B-cells, allowing the radioactive yttrium to destroy the cell via production of beta particles.

Dosage forms of Ibritumomab tiuxetan

FormRouteStrength
Kit for radiopharmaceutica l preparation for infusionIntravenous use1.6 mg/ml
Prescription Generics

false

International Brands

Zevalin

Synonyms

Ibritumomab mAb Murine (IGG1) Anti P19437 (CD20_MOUSE)

Manufacturers

Spectrum Pharmaceuticals, Inc.

CAS number

206181-63-7

UNII

4Q52C550XK

State

liquid

Affected organisms

Humans and other mammals

Indication of Ibritumomab tiuxetan

For treatment of non-Hodgkin’s lymphoma

Toxicity of Ibritumomab tiuxetan

RX24 Drugs Disclaimer: before buying a Ibritumomab tiuxetan on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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