Save up -80% on Ibuprofen
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Advil
|$4.03||100 tablets/200 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Advil coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Ibuprofen every time. What are you waiting for? Claim your prescription drug card now!
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Ibuprofen volume of distribution
Protein binding is saturable and at concentrations >20 μ g/mL binding is non-linear. Based on oral dosing data there is an age- or fever- related change in volume of distribution for ibuprofen. Febrile children <11 years old have a volume of approximately 0.2 L/kg while adults have a volume of approximately 0.12 L/kg.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ibuprofen
Ibuprofen, a propionic acid derivative, is a prototypical nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Ibuprofen mechanism of action
The exact mechanism of action of ibuprofen is unknown. Ibuprofen is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 (COX-2) which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Ibuprofen is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer i in vivo /i . The S-enantiomer is believed to be the more pharmacologically active enantiomer.
Dosage forms of Ibuprofen
|Advil Liqui Gels||200mg||72 Liquid Gel Caps||$30.00|
|Advil Liqui Gels Extra Strength||400mg||50 Liquid Gel Caps||$45.00|
|Advil OTC||200mg||100 Tablet||$19.86|
|Advil Pediatric Drops Fruit||50mg/1.25mL||24mL Suspension-Fruit Alcohol Free||$18.49|
|Motrin Children/Infant Drops||50mg/1.25mL||15mL Drops||$13.53|
|Robax Platinum||500/200mg||18 Tablet||$37.00|
|Robax Platinum||500/200mg||60 Tablet||$61.00|
10 Person Ansi
(+-)-2-(P-Isobutylphenyl)propionic acid (+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
Genuine First Aid LLC
Humans and other mammals
Indication of Ibuprofen
For symptomatic treatment of rheumatoid arthritis, juvenile rheumatoid arthritis and osteoarthritis. May be used to treat mild to moderate pain and for the management of dysmenorrhea. May be used to reduce fever. Has been used with some success for treating ankylosing spondylitis, gout and psoriatic arthritis. May reduce pain, fever and inflammation of pericarditis. May be used IV with opiates to relieve moderate to severe pain. Ibuprofen lysine may be used IV to treat patent ductus arteriosus (PDA) in premature neonates.
Toxicity of Ibuprofen
p Side effects: May cause peripheral edema and fluid retention. Use caution in patients with congestive heart failure or severe uncontrolled hypertension. May cause dyspepsia, heartburn, nausea, vomiting, anorexia, diarrhea, constipation, stomatitis, flatulence, bloating, epigastric pain, and abdominal pain. Peptic ulcer and GI bleeding have been reported. May also cause dizziness, headache and nervousness. Acute renal failure accompanied by acute tubular necrosis has been reported. p Most common symptoms of overdose are abdominal pain, nausea, vomiting, lethargy, vertigo, drowsiness (somnolence), dizziness and insomnia. Other symptoms of overdose include headache, loss of consciousness, tinnitus, CNS depression, convulsions and seizures. May rarely cause metabolic acidosis, abnormal hepatic function, hyperkalemia, renal failure, dyspnea, respiratory depression, coma, acute renal failure, and apnea (primarily in very young pediatric patients). /p p LD sub 50 /sub =1255mg/kg(orally in mice) /p
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What is Advil?
Advil is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body. Advil is used to reduce the temperature and treat pain or inflammation caused by many conditions, such as headache, toothache, back pain, arthritis, menstrual cramps, or minor trauma.
Advil may increase the risk of a fatal heart attack or stroke, especially if you use it for a long time or take high doses, or if you have heart disease. Do not use this medicine immediately before or after heart bypass surgery (coronary artery bypass surgery or CABG).
Advil can also cause stomach or intestinal bleeding, which can be fatal. These conditions may occur without warning when you use ibuprofen, especially in older people. Do not take more than the recommended dose. Advil overdose can damage your stomach or intestines. Use only the smallest amount of medication needed to relieve pain, swelling, or fever.