Save up -80% on Icodextrin

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Icodextrin

Extraneal icodextrin dial soln

$0.05

ml

* price without discount in nearest pharmacy. Price may vary.

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Icodextrin volume of distribution

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What is Icodextrin

Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.

Icodextrin mechanism of action

Icodextrin is a starch-derived, water-soluble glucose polymer linked by alpha (1-4) and alpha (1-6) glycosidic bonds with an average molecular weight between 13,000 and 19,000 daltons. It functions as a colloid osmotic agent to achieve ultrafiltration during long (12-16 hour) peritoneal dialysis dwells. In other words it helps clean waste out of the body when the kidneys are not functioning properly. Icodectrin acts in the peritoneal cavity by exerting osmotic pressure across small intercellular pores resulting in transcapillary ultrafiltration through the dwell. This is due to the fact that the polymer is minimially absorbed across the peritoneal membrane. Icodextrin achieves superior fluid removal compared with glucose-based dialysates.

Dosage forms of Icodextrin

FormRouteStrength
Injection, solutionintraperitoneal
Solutionintraperitoneal
Prescription Generics

false

International Brands

Extraneal

Synonyms

Icodextrin Icodextrina

Manufacturers

Baxter Corporation

CAS number

337376-15-5

UNII

2NX48Z0A9G

State

solid

Affected organisms

Humans and other mammals

Indication of Icodextrin

Used for continuous ambulatory peritoneal dialysis (CAPD) of diabetic patients or automated peritoneal dialysis (APD) for the management of end-stage renal disease.

Toxicity of Icodextrin

RX24 Drugs Disclaimer: before buying a Icodextrin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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