Save up -80% on Icosapent ethyl
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Vascepa
|$245.91||120 capsules/1 g|
|price without discount in nearest pharmacy. Price may vary.|
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Icosapent ethyl volume of distribution
The mean volume of distribution at steady-state of EPA is approximately 88 liters. The majority of EPA circulating in plasma is incorporated in phospholipids, triglycerides and cholesteryl esters, and <1% is present as the unesterified fatty acid.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Icosapent ethyl
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as adjunct therapy for severe hypertriglyceridemia (TG levels 500 mg/dL). FDA approved on July 26, 2012.
Icosapent ethyl mechanism of action
Studies suggest that EPA reduces hepatic very low-density lipoprotein triglycerides (VLDL-TG) synthesis and/or secretion and enhances TG clearance from circulating VLDL particles. Potential mechanisms of action include increased -oxidation; inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase (DGAT); decreased lipogenesis in the liver; and increased plasma lipoprotein lipase activity.
Dosage forms of Icosapent ethyl
EPA ethyl ester Epadel S
Amarin Pharma Inc.
Humans and other mammals
Indication of Icosapent ethyl
Icosapent ethyl is used as adjunct therapy to reduce triglyceride (TG) levels in adults with severe (500 mg/dL) hypertriglyceridemia.
Toxicity of Icosapent ethyl
Icosapent ethyl is generally well tolerated and adverse effects are unrelated to treatment.
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What is Vascepa?
Vascepa works in the liver and bloodstream to reduce low density triglycerides. Vascepa is used in conjunction with a low-fat, low-cholesterol diet to lower triglycerides (fats) in adults with very high triglycerides.
It is not known whether Vascepa will reduce the risk of developing heart disease or pancreatitis (inflammation of the pancreas). Vascepa is used along with a low-fat diet and other treatments to lower total cholesterol in people with high cholesterol.
Before taking Vascepa, tell your doctor if you have liver disease, diabetes, thyroid disorder, pancreatic problems, bleeding or blood disorders, are allergic to fish or shellfish, or if you drink large amounts of alcohol. Vascepa is only part of a treatment program that can also include diet, exercise, and weight control. Follow your doctor’s instructions very carefully.