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Price of Idoxuridine
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Idoxuridine volume of distribution
What is Idoxuridine
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent. (PubChem)
Idoxuridine mechanism of action
Idoxuridine acts as an antiviral agent by inhibiting viral replication by substituting itself for thymidine in viral DNA. This in turn inhibits thymidylate phosphorylase and viral DNA polymerases from properly functioning. The effect of Idoxuridine results in the inability of the virus to reproduce or to infect/destroy tissue.
Dosage forms of Idoxuridine
Herpes simplex virus
Indication of Idoxuridine
For use in keratoconjunctivitis and keratitis caused by herpes simplex virus.
Toxicity of Idoxuridine
Hypersensitivity or increased sensitivity of eyes to light. LD sub 50 /sub =3080 mg/kg (orally in mice).
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