Save up -80% on Iloprost
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Ventavis
|$4,008.99||1 carton (30 ampules) 10mcg/ml|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Ventavis coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Iloprost every time. What are you waiting for? Claim your prescription drug card now!
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Iloprost volume of distribution
Following intravenous infusion, the apparent steady-state volume of distribution was 0.6 to 0.8 L/kg in healthy subjects. Total plasma protein binding of iloprost is concentration independent in the range of 30 to 3000 picograms/mL and amounts to approximately 60%, of which 75% is due to albumin binding.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Iloprost
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Iloprost mechanism of action
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, such as carbaprostacyclin. Iloprost binds with equal affinity to human prostacyclin (Prostanoid IP) and prostaglandin EP1 receptors. Iloprost constricts the ilium and fundus circular smooth muscle as strongly as prostaglandin E2 (PGE2) itself. Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. All of these properties help to antagonize the pathological changes that take place in the small pulmonary arteries of patients with pulmonary hypertension.
Dosage forms of Iloprost
|Nebuliser solution||Inhalation use||10 .g/ml|
|Nebuliser solution||Inhalation use||20 .g/ml|
|Solution||respiratory (inhalation)||.01 mg/mL|
Actelion Pharmaceuticals US, Inc.
Humans and other mammals
Indication of Iloprost
Used for the treatment of pulmonary arterial hypertension.
Toxicity of Iloprost
Overdoses can lead to hypotension, headache, flushing, nausea, vomiting, and diarrhea.
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