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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ventavis

$4,008.991 carton (30 ampules) 10mcg/ml
Price with discount in nearest pharmacy. Price may vary.

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Iloprost volume of distribution

Following intravenous infusion, the apparent steady-state volume of distribution was 0.6 to 0.8 L/kg in healthy subjects. Total plasma protein binding of iloprost is concentration independent in the range of 30 to 3000 picograms/mL and amounts to approximately 60%, of which 75% is due to albumin binding.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Iloprost

Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).

Iloprost mechanism of action

Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, such as carbaprostacyclin. Iloprost binds with equal affinity to human prostacyclin (Prostanoid IP) and prostaglandin EP1 receptors. Iloprost constricts the ilium and fundus circular smooth muscle as strongly as prostaglandin E2 (PGE2) itself. Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. All of these properties help to antagonize the pathological changes that take place in the small pulmonary arteries of patients with pulmonary hypertension.

Dosage forms of Iloprost

Nebuliser solutionInhalation use10 .g/ml
Nebuliser solutionInhalation use20 .g/ml
Solutionrespiratory (inhalation).01 mg/mL

Prescription Generics


International Brands




Actelion Pharmaceuticals US, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Iloprost

Used for the treatment of pulmonary arterial hypertension.

Toxicity of Iloprost

Overdoses can lead to hypotension, headache, flushing, nausea, vomiting, and diarrhea.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Iloprost on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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