Save up -80% on Infliximab

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Remicade

$1,164.531 vial/100mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Remicade coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Infliximab every time. What are you waiting for? Claim your prescription drug card now!

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Infliximab volume of distribution

The volume of distribution of infliximab is low and at steady state ranges from 4.5 to 6 L. Therapeutic monoclonal antibodies, such as immunoglobulins, are cleared from the circulation primarily by catabolism. Median infliximab half-life is approximately 14 days.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Infliximab

Tumor necrosis factor (TNF-alpha) binding antibody (chimeric IgG1). It is composed of human constant and murine variable regions. Infliximab is produced by a recombinant cell line cultured by continuous perfusion

Infliximab mechanism of action

Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with its receptors. Infliximab does not neutralize TNFb (lymphotoxin a), a related cytokine that utilizes the same receptors as TNFa. TNFa activation normally induces the release of proinflammatory cytokines, the enhancement of leukocyte migration and activation of neutrophils among others. Neutralization of the biological activity of TNFa leads to an overall reduction in inflammation.

Dosage forms of Infliximab

FormRouteStrength
Powder for concentrate for solution for infusionIntravenous use100 mg
Injection, powder, lyophilized, for solutionintravenous100 mg/10mL
Powder for solutionintravenous100 mg

Prescription Generics

false

International Brands

Inflectra

Synonyms

Ig gamma-1 chain C region

Manufacturers

Celltrion Healthcare Co Ltd

CAS number

170277-31-3

UNII

B72HH48FLU

State

liquid

Affected organisms

Humans and other mammals

Indication of Infliximab

To manage the signs and symptoms, as well as to induce and maintain clinical remission in adults with moderate to severe active Crohn’s disease or ulcerative colitis. Also used to manage signs and symptoms of rheumatoid arthritis (in conjunction with methotrexate), ankylosing spondylitis, psoriatic arthritis, and juvenile arthritis.

Toxicity of Infliximab

Furthermore, concurrent use of other immunosuppresive agents, such as 6-mercaptopurine, may reduce the incidence of less serious side effects, such as arthralgias, myopathies and other antibody-associated diseases. Since its approval, infliximab has revolutionised the treatment of Crohn’s disease and has shown benefit in a variety of other inflammatory conditions, but significant toxicities can occur that necessitate thorough screening protocols and periodic clinical evaluation.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Infliximab on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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