Save up -80% on Infliximab

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Infliximab

Remicade 100 mg vial

$789.44

vial

* price without discount in nearest pharmacy. Price may vary.

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Infliximab volume of distribution

3-6 L

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What is Infliximab

Tumor necrosis factor (TNF-alpha) binding antibody (chimeric IgG1). It is composed of human constant and murine variable regions. Infliximab is produced by a recombinant cell line cultured by continuous perfusion

Infliximab mechanism of action

Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with its receptors. Infliximab does not neutralize TNFb (lymphotoxin a), a related cytokine that utilizes the same receptors as TNFa. TNFa activation normally induces the release of proinflammatory cytokines, the enhancement of leukocyte migration and activation of neutrophils among others. Neutralization of the biological activity of TNFa leads to an overall reduction in inflammation.

Dosage forms of Infliximab

FormRouteStrength
Powder for concentrate for solution for infusionIntravenous use100 mg
Injection, powder, lyophilized, for solutionintravenous100 mg/10mL
Powder for solutionintravenous100 mg
Prescription Generics

false

International Brands

Inflectra

Synonyms

Ig gamma-1 chain C region

Manufacturers

Celltrion Healthcare Co Ltd

CAS number

170277-31-3

UNII

B72HH48FLU

State

liquid

Affected organisms

Humans and other mammals

Indication of Infliximab

To manage the signs and symptoms, as well as to induce and maintain clinical remission in adults with moderate to severe active Crohn’s disease or ulcerative colitis. Also used to manage signs and symptoms of rheumatoid arthritis (in conjunction with methotrexate), ankylosing spondylitis, psoriatic arthritis, and juvenile arthritis.

Toxicity of Infliximab

RX24 Drugs Disclaimer: before buying a Infliximab on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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