Save up -80% on Interferon Alfa-2a, Recombinant

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Interferon Alfa-2a, Recombinant


$1060180 mcg/mL
price without discount in nearest pharmacy. Price may vary.

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Interferon Alfa-2a, Recombinant volume of distribution

* 0.223 to 0.748 L/kg healthy people

RX Prescription
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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Interferon Alfa-2a, Recombinant

Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.

Interferon Alfa-2a, Recombinant mechanism of action

Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which, upon dimerization, activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription)which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.

Dosage forms of Interferon Alfa-2a, Recombinant

Liquidintramuscular; subcutaneous6000000 unit
Powder for solutionintramuscular; subcutaneous18000000 unit
Powder for solutionintramuscular; subcutaneous3000000 unit

Prescription Generics


International Brands

Roferon A Soln Inj 6 Million


Interferon alfa-2a Interferon alfa-2a (recombinant)


Hoffmann La Roche Limited

CAS number






Affected organisms

Humans and other mammals

Indication of Interferon Alfa-2a, Recombinant

For the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi’s sarcoma, and chronic myelogenous leukemia. Also for the treatment of oral warts arising from HIV infection.

Toxicity of Interferon Alfa-2a, Recombinant

Interferon alfa-2 may cause serious adverse effects such as anemia; autoimmune diseases, including vasculitis, arthritis, hemolytic anemia, and erythematosus syndrome; cardiotoxicity; hepatotoxicity; hyperthyroidism or hypothyroidism; transient ischemic attacks; leukopenia; neurotoxicity; peripheral neuropathy; and thrombocytopenia. Some lesser side effects that may not need medical attention include blurred vision, change in taste or metallic taste, cold sores or stomatitis, diarrhea, dizziness, dry mouth, dry skin or itching, flu-like syndrome, increased sweating, leg cramps, loss of appetite, nausea or vomiting, skin rash, unusual tiredness, weight loss, and partial loss of hair.

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