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Price of Interferon alfa-n3
Alferon n 5 million unit vial
* price without discount in nearest pharmacy. Price may vary.
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Interferon alfa-n3 volume of distribution
What is Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Interferon alfa-n3 mechanism of action
Interferon alpha binds to type I interferon receptors (IFNAR1 and IFNAR2c) which, upon dimerization, activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription) which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon alpha binds less stably to type I interferon receptors than interferon beta.
Dosage forms of Interferon alfa-n3
Hemispherx Biopharma, Inc
Humans and other mammals
Indication of Interferon alfa-n3
For the intralesional treatment of refractory or recurring external condylomata acuminata.
Toxicity of Interferon alfa-n3
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